Blade: Trinity (2004)

This is an imperfect-but-creditable movie. In the media, Blade (Wesley Snipes) is portrayed as a delusional serial killer who uses a fantasy about a secret group of vampires to justify his murders. The vampire leaders have infiltrated the FBI and catch Blade in a raid. After escaping he teams up with the Nightstalkers, who are a group of humans trying to kill the vampires. Their blind scientist (Natasha Lyonne) develops an airborne virus that attacks vampire DNA that has evolved away from the pure line of Dracula.

Spike television ran a 12 episode series in 2006 that continued the story from the films. There are three version of the final scene: theatrical ending, unrated ending, and werewolf ending. The film's overall gross was less than what Blade II earned. This was the first film in the series to have the Marvel Studios logo at the beginning. Vampire enforcer Jarko Grimwood is played by wrestler Triple H. In the scene when Hedge (Patton Oswalt) is introduced, he is wearing a Fantastic Four t-shirt.