Underworld: Awakening (2012)

This is a solid movie. Humans capture the priority vampire target, Selene (Kate Beckinsale), during a global military crusade to exterminate vampires and lycans. Twelve years later, Selene, dubbed Subject 1, is freed from cryogenic suspension by Subject 2 and escapes. She learns that the second patient is a young girl who is the offspring of Selene and vampire-lycan hybrid Michael Corvin. Fellow vampire David takes Selene and her daughter to his coven, but his father disapproves of the decision. Meanwhile, Dr. Jacob Lane, who is secretly a lycan has been working on a drug designed to make lycans immune to the deadly effects of silver.

This is the fourth film in the series.