I am Legend (2007)

This is a noteworthy movie. In 2009 a virus was developed that is able to cure cancer, but it quickly changes into a deadly disease. The new virus has a kill ratio of 90% and only 1% of people are immune, but most of the survivors turn into violent mutants afraid of sunlight. After three years, military virologist Robert Neville (Will Smith) believes he is the only healthy person still alive in New York City. His only companion is a female German Shepherd named Samantha. He maintains a lab in the basement of his home where he performs experiments hoping to find a cure to the destructive illness.

A $5 million scene at the Brooklyn Bridge was the most expensive ever filmed in New York City at the time. The scene had to meet requirements from fourteen government agencies. The film opened to the largest ever box office (not adjusted for inflation) for a non-Christmas film released in December. It is the third feature film adaptation of Richard Matheson's 1954 novel of the same name, following The Last Man on Earth (1964) and The Omega Man (1971). Abbey and Kona, both three-year-old German Shepherd Dogs, played Neville's dog Sam. Willow Smith, Will Smith's daughter, makes her film debut as Marley, Neville's daughter.

Popular Mechanics wrote an article about the film: I Am Legend's Junk Science: Hollywood Sci-Fi vs. Reality